Conclusion:
COVID-19-associated neurological manifestations are widely reported, with some rare instances of anti-MOG syndrome in coexistence with SARS-CoV-2 infection. We report the first case of concurrent NMOSD and IIH in the context of COVID-19 infection. While the propensity for triggering autoantibody production and thrombophilic disorders is prevalent in COVID-19, physicians and neurologists must be vigilant with low threshold to further investigate the possibility of secondary idiopathic intracranial hypertension and demyelinating disorders in patients presenting with headache and decreased visual acuity following recent COVID-19 infection.