Higher Th22 cell counts in children with FLG mutations
Children with FLG mutation had higher Th22 cell numbers compared
to children of the wild-type population (Figure 2A, eTable1). The median
cell number within the FLG mutation group was 5.60/μL (IQR
4.04;8.94) and within the wild-type group 4.54/μL (IQR 2.50;7.38, p
=0.03). In contrast, when studying this association in the atopic
dermatitis population, no significant associations were observed
(eFigure 1A).