p values: Log Rank Test.
High risk patients were further analyzed for the factors affecting biochemical recurrence free survival with multivariate analysis. Cox regression analysis including patients’ waiting period, PSA value at the time of diagnosis, Gleason grade groups in prostate biopsy and radical prostatectomy specimens, presence of positive surgical margins and/or having SV invasion demonstrated the main factor affecting time to PSA progression in high risk patients as SV invasion (p<0.001 HR:2.51 CI: 1,58-4,45). Other factors including time to surgery(p=0.156 HR:0.63 CI:0.33-1.19) did not have any statistically significant impact on outcome.