An unusual story of electrical storm on the graft.
Etienne Charbonneau¹, ², MD, Céline
Chabanne¹, ², MD, Bernard Lelong¹,², MD, Vincent Galand ², MD, Erwan Flécher¹, MD, PhD.
¹Department of cardiothoracic and vascular surgery, Rennes University
Hospital, Rennes, France
²Department of cardiology, Rennes University Hospital, Rennes, France.
The data that support the findings of this study are openly available in
Journal of Cardiac Surgery at http://doi.org/[doi], reference number
[reference number].
Corresponding Author:
Dr Etienne Charbonneau
Departement of Cardiology
CHU Pontchaillou
2 henri Le Guilloux St
35 000 Rennes, France
Tel : +33648883662
Email
: echarbonneau@hotmail.fr
Declarations of interest: none
Funding : none
AbstractBackground: Cancers, and specifically lymphomas, are one of the main
causes of morbidity and mortality after heart transplant. We encountered
this complication on a 54-year-old male patient, which brought to our
attention the lack of a specific and appropriate treatment for a primary
cardiac lymphoma on the graft.
Objective: This case report highlights the challenging management of
primitive heart transplant lymphoma and its treatment.
Method: electronic medical record literature reviewed through Pubmed
interface of Medline.
This study was approved by the CHU Rennes Ethics Committee.
Written informed consent was obtained from the patient for the
publication of this case report.
Result: We report the case of an Epstein-Barr Virus (EBV) induced
primary cardiac lymphoma on the graft. The lymphoma spread quickly in
spite of the numerous treatments we tried and resulted in rhythmic
complication. Endocavitary implantable cardioverter defibrillator was
implanted but quickly removed due to local complications. The patient
died from a sudden death at home shortly after.
Conclusions: Primary cardiac lymphoma on the graft is highly rare with
poor prognosis and rhythmic complications. Further studies are needed to
assess the benefits of other treatment approaches, such as
radiofrequency ablation techniques.
Keywords: lymphoma, heart transplant, ventricular arythmia,
electrical storm.
Abbreviations; ICD: implantable cardioverter defibrillator, EBV: ebstein
bar virus, TV: ventricular tachycardia, CICU: Cardiac Intensive Care
Unit.