Acknowledgements
The authors would like to thank Ms. M Matsumura, Ms. K Yin, and Ms. F Saito (The University of Tokyo) for their technical assistance.
This work was supported by Grants-in-Aid for Scientific Research from the Japan Society for the Promotion of Science (KAKENHI; grant nos. JP17H04224, JP18K19467, and JP20H00528 to J.T. and JP26221308 and JP19H05656 to S.O.); Project for Cancer Research and Therapeutic Evolution (P-CREATE; grant no. JP19cm0106509h9904 to J.T.), Project for Development of Innovative Research on Cancer Therapeutics (P-DIRECT; grant no. JP20cm0106501h0005 to S.O.), and Practical Research for Innovative Cancer Control (grant no. JP19ck0106468h0001 to J.T.) from Japan Agency for Medical Research and Development (AMED); Princess Takamatsu Cancer Research Fund (grant to J.T.).