Description of population
Of the 167 inpatients invited to participate in our study, a total of 14
were excluded for the following reasons: 6 due to lack of consent, 5 due
to incomplete laboratory and 3 due to incomplete personal data. Finally,
our study population consisted of 153 inpatients, of which 59.5% were
male and 40.5% female, with mean age at admission 3.6 months
(SD+ 2.8). The median level of serum 25(OH)D was 51.4 nmol/L
(IQR:29.7-72.2). Specifically, 25.9% of inpatients had serum 25(OH)D
levels <30 nmol/L, 19.6% 30-50 nmol/L and 54.4%
>50 nmol/L. The median nasal LL-37 levels were 17.1 ng/mg
of total protein (IQR:6.4-40.2) and those of β-defensin-2 were 157.7
ng/mg of total protein (IQR:104.5-250.2). O2supplementation was recorded in 89.5% of our patients, IV fluid
administration in 58.8%, NG feeds in 15.7% and use of medications
(inhaled medication or antibiotics) in 73.2%. The median maximum
modified Wang score was 4 (IQR:3-5) and the median duration of
hospitalization 5 days (ΙQR:3-7). Finally, 6.5% of our patients were
admitted to ICU and 1.3% were intubated.
Supplemental population description is shown in Table 1.