FIGURE LEGENDS
Figure 1 . Study Flow Diagram.
Figure 2. Risk of Bias Summary. Each study included in the meta-analysis was assessed for risk of bias based on whether the various measures as shown in the figure were satisfied. Question marks within yellow circles indicate that it was not clear whether the study satisfied the measure. Plus signs within green circles indicate that the study satisfied the measure. Minus signs within red circles indicate that the study did not satisfy the measure. The EPPIC-1 and EPPIC-2 trials were combined under “Schulman 2015” as shown in the figure.
Figure 3. Comparison of the Effect of AST-120 versus Control on All-cause Mortality.
Figure 4. Comparison of the Effect of AST-120 versus Control on the Incidence of End-stage Renal Disease Requiring Renal Replacement Therapy.
Figure 5. Comparison of the Effect of AST-120 versus Control on Serum Creatinine Levels.
Table 1 Characteristics of Studies Included in the Meta-analysis