2.1 Ethics
All procedures during this clinical study were performed according to the Code of Practice for the Conduct of Clinical trials for Veterinary Medical Products and the Guide for the Care and Use of Agricultural Animals in Research and Teaching, and the animals were maintained in accordance with National and European animal Welfare requirements (OECD 2000, EMEA 2001, EC 2003, FASS 2010). All animal procedures regarding animal care and use were approved by the Ethical Committee of the Faculty of Veterinary Medicine, School of Health Sciences, University of Thessaly (Approval number: 65/26-02-2019).