2.1 Ethics
All procedures during this clinical study were performed according to
the Code of Practice for the Conduct of Clinical trials for Veterinary
Medical Products and the Guide for the Care and Use of Agricultural
Animals in Research and Teaching, and the animals were maintained in
accordance with National and European animal Welfare requirements (OECD
2000, EMEA 2001, EC 2003, FASS 2010). All animal procedures regarding
animal care and use were approved by the Ethical Committee of the
Faculty of Veterinary Medicine, School of Health Sciences, University of
Thessaly (Approval number: 65/26-02-2019).