Intra-operative parameters
Intra-operative data (i.e., duration of operation, minute-by-minute
temperature recordings, intravenous agents employed, intra-operation
complications and ICU admission) were available for 108 patients
(Table 1 ). According to
these, the duration of anesthesia was significantly longer in the IOH
group compared to the NIOH group (289 min and 189 min, respectively).
One of the patients in the IOH group was admitted to the ICU with
suspected malignant hyperthermia and his operation was stopped after 182
minutes.
There was no significant difference in temperatures at the beginning of
the operations between the IOH and NIOH groups (35.9°C and 35.8°C,
respectively; p = 0.639); however, statistical significance was observed
for temperature at the end of the operation between the groups (38.3°C
IOH and 36.7°C NIOH; p < 0.001).
Peak
temperature measured in the IOH group was 38.3°C, and peak temperature
measured in the NIOH group was 36.9°C (p < 0.001).
A positive and significant correlation was found between body
temperature and duration of surgery (p < 0.05), as well as
between peak temperature during the operation and the duration of the
operation (p < 0.001) (Figure 1 ). Two patients were
admitted to the ICU: one due to suspected malignant hyperthermia (IOH
group) and the other due to low oxygen saturation during the operation
(NIOH group).
Intravenous agents used during the operation included Propofol,
Perfalgan, Neostigmine, Atropine, Midazolam, Emerone, Tracium and
Morphine; no differences were evident in the use of these agents between
the IOH and NIOH groups.