Affiliations:
College of Veterinary Medicine, South China Agricultural University, Guangzhou, China;
Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Scientific Observation and Experiment Station of Veterinary Drugs and Diagnostic Techniques of Guangdong Province, Ministry of Agriculture of Rural Affairs, and Key Laboratory of Animal Disease Prevention of Guangdong Province, Guangzhou, 510640, China.
Address for correspondence:
Shao-Lun Zhai, Animal Disease Diagnostic Center, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China, zhaishaolun@163.com; Dong-Sheng He, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China, dhe@scau.edu.cn.
Abstract: Seneca Valley virus (SVV) is an emerging picornavirus, which mainly affects swine health. However, previous studies showed that mice could be infected by SVV. In addition, the antibodies against SVV were detected in bovine blood. The data reveal the possible cross-species transmission of SVV. In this study, one SVV strain (SVA/GD/China/2018) was first isolated from a buffalo farm in Guangdong, China, using seven mammalian cell lines. Compared with the 35 reference SVV strains, sequence analysis showed that SVA/GD/China/2018 shared 93.4%–99.1% and 97.5%–99.4% similarity in complete genome level and polyprotein gene level, respectively. Interestingly, SVA/GD/China/2018 shared the highest nucleotide similarity (99.1%) with one wild boar strain (Sichuan HS-01). Genetic analysis revealed that SVA/GD/China/2018 clustered with the porcine-origin SVV strains. Isolation of SVV in buffalo further supported potential cross-species transmission of SVV.
Keywords: Seneca Valley virus; porcine; buffalo; cross-species transmission