Methods
This is a one-year prospective study. Total 20 consequent infants who full fill a) age less than 3-year-old, b) a clinical schedule for elective FB, and c) got parents signed-consent were enrolled. Two bronchoscopists (Soong and Chen) carried out these SPI studies. The Institutional Review Board of hospital and IRB approved this study (DMR-109-179, CMUH108-REC3-114). Patient confidentiality was maintained in accordance with Health Insurance Portability and Accountability Act guidelines.
The study child was supine lie on the endoscopy room table, setting with procedural sedation and continuous cardiopulmonary monitoring as usual doing FB. A continuous oxygen flow (1.0 L/Kg/min, maximal 10.0 L/min) delivered via a small nasopharyngeal catheter via (right) nostril as the “PhO2”. This NIV of PhO2-NC-AC supported the whole FB intervention.
All the SPI studies were performed after completion of their original scheduled FB. Figure 1a shows the configuration of this study. A short (25 cm) working-length FB (OD 3.8mm, HYF-V, Olympus), with an inner channel (1.2 mm), inserted via one side (left) nostril. A small pressure transmitting catheter links the inner channel to a real-time pressure monitor (GB30, Galemed, Taiwan). Therefore, the real-time dynamic intra-pharyngeal pressures could be measured when the FB tip freely located in the PLS.