The second barley-OFC after OIT for wheat
Among nine patients with positive results to the first barley-OFCs, two
patients enrolled slow OIT while seven enrolled rush OIT for wheat
(Table 2). Wheat-OFCs results before OIT are shown in Table S1. All
patients achieved desensitized status to a daily amount of wheat
products (equivalent to 2,000 mg wheat protein) within three years.
The second barley-OFC was performed at a median of 2 (range: 1.1–5.5)
years after the first barley-OFCs (Table 2). The results were negative
for all nine patients. The median amount of desensitized wheat protein
was 5,580 mg (range: 2046–7800) at the second barley-OFC. The sIgE
titers to omega-5 gliadin after wheat OIT significantly decreased
compared to before OIT (Table 3). On the other hand, the change in
barley-sIgE was not uniform (reduction: 5 patients, elevation: 2
patients, no data: 2 patients).