Introduction
Tenofovir is a nucleotide reverse transcription inhibitor. It is widely used for the treatment of HIV and Hepatitis B. The most common side effect of the drug is gastrointestinal which is usually mild.1,2 Other side effects include hepatic, nephrological, pancreatitis, Fanconi’s anemia, diabetes insipidus, and pneumonia.2,3 The incidence of cutaneous adverse effects ranges from 5% to 18%. However, they have not been well documented.4,5 Tenofovir is the least suspected drug for cutaneous side effects as there are many other anti-viral medications used for the treatment of HIV with well-documented adverse effects. Only two cases of Leukocytoclastic vasculitis due to tenofovir have been reported to date. Here, we present a third case and also review the cutaneous side effects of tenofovir.