Table 3. Overall results of meta-analysis Table 3. Overall results of meta-analysis Table 3. Overall results of meta-analysis Table 3. Overall results of meta-analysis Table 3. Overall results of meta-analysis Table 3. Overall results of meta-analysis Table 3. Overall results of meta-analysis Table 3. Overall results of meta-analysis Table 3. Overall results of meta-analysis Table 3. Overall results of meta-analysis Table 3. Overall results of meta-analysis Table 3. Overall results of meta-analysis
Outcome N N N Overall effect Overall effect Overall effect Overall effect Heterogeneity Heterogeneity Heterogeneity
Studies MI MS IRR SMD RD 95%CI p χ2 p I2
Primary outcome
Late mortality 6 0.98 0.25; 3.82 0.98 1.5 0.91 0%
Late relapse 6 1.13 0.26; 4.88 0.87 0.68 1 0%
Secondary outcome
Early mortality 11 294 359 0 -0.02; 0.02 1 0 1 0
Bleeding 11 294 359 -0.01 -0.03; 0.01 0.59 1.88 1 0%
Respiratory failure 11 294 359 -0.00 -0.02; 0.01 0.6 1.98 1 0%
Renal failure 11 294 359 -0.00 -0.02; 0.01 0.62 3.39 0.97 0%
Neuro Complication 11 294 359 -0.01 -0.03; 0.01 0.22 8.34 0.60 0%
Length of staya 10 292 356 -1.59 -2.35; -0.82 <. 01 152.42 <. 01 94%
CPB timea 10 292 356 0.73 0.32; 1.13 <. 01 49.86 <. 01 82%
Cross clamp timea 10 292 356 0.32 0.08; 0.56 .03 18.97 <. 01 53%
Late redo-surgery 6 1.92 0.39; 9.53 0.42 0.41 1 0%
Tumor size 7 229 255 -0.47 -1.29; 0.35 0.26 100.3 <. 01 94%
CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality. CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality. CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality. CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality. CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality. CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality. CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality. CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality. CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality. CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality. CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality. CI=Confidence interval. CPB=Cardiopulmonary bypass. IRR=Incidence rate ratio. MI=Minimally invasive. MS=Median sternotomy. RD=Risk difference. SMD=Standardized mean difference. a Denotes significance. Include in-hospital and 30-days mortality.