Conclusion
This study documented the incidence, clinical course, and outcomes of
pregnancy-related GAS infection and sought to elucidate the factors
associated with infection severity. Deferral of medical intervention of
more than 24 hours from the first signs of infection had the most
important impact upon maternal deterioration. Antibiotic prophylaxis
during labour may reduce GAS complications, warranting further study to
detect specific risk factors and to reassess GAS screening, antibiotic
prophylaxis and prevention policies.