Six-month Follow-up after Ablation
All 19 patients demonstrated improvement in symptoms. The NYHA
functional class improved from NYHA III (2-3) to NYHA II (1-2) (p
< 0.001). There was a favorable hemodynamic effect, with
reduction or elimination of the outflow obstruction at the 6-month
follow-up with the resting LVOT gradient decreased from 87.6 ± 29.5 mmHg
to 48.1 ± 29.7 mmHg (p < 0.001) (Figure 1F, 5A). No
significant change was present in the IVS thickness and LA diameter
after six months of follow-up, respectively (20.3 ± 6.5 mm vs. 20.1 ±
6.7 mm, p = 0.6), (42.6 ± 5.8 mm vs. 41.7 ± 6.6 mm, p = 0.1). Four
dimensions (physical functioning, role-physical, general health, and
reported health transition) of the SF36 quality-of-life index had values
that increased after six months follow-up (Figure 5B).
The reduction of gradient was greater in patients with limited basal
septal hypertrophy (60.9 ± 8.3mm vs. 27.9 ± 7.1mm, p = 0.01) and shorter
AML (56.1 ± 6.4mm vs. 20.4 ± 5.0mm, p<0.01). For patients with
DPM, the reduction of gradient was lower than others (36.9 ± 7.1mm vs.
75.0 ± 6.3mm, p <0.05) (Figure 6).