Figure 4
CD23 as an inhibitor of allergic sensitisation. CD23 plays different
roles during the allergic response including A) clearance of serum IgE
that counteracts the allergic pathway to prevent IgE sensitization on
FcɛRI B) negative feedback regulation of IgE synthesis by binding of
IgE-ICs to CD23 on B cells C) T cell proliferation and antibody
production induced by binding of IgE-ICs to CD23 on B cells.