IMPACT STATEMENT
Improving the understanding of the pathophysiology of allergy and
relationship with otitis media is important to develop preventive
measures as well as perform adequate monitoring and treatment
of children with allergy and otitismedia with effusion,although futures
studies are required to increase evidence supporting that anti-allergy
treatment may improve resolution and outcome of OME. The evidence
linking atopy or allergy to other phenotypes is poor and contradictory
and further studies are needed, paying particular attention to accurate
phenotyping of otitis media.
TABLE1. Laboratory evidence and biomarkers linking allergy to OME.