METHODS
Using MEDLINE/PubMed, Scopus and the Cochrane Library, we performed searches of case reports and clinical studies published until 30 October 2020. Eligible studies were identified using various combinations of Medical Subject Headings and keywords in the abstract or title: Impella, aortic regurgitation, mitral regurgitation, aortic valve injury, mitral valve injury, and mechanical circulatory support. Ethics Committee approval was not required as this is a review manuscript.