Animal Preparation 
This pilot study was conducted on six male Yorkshire pigs (Kg 50.2+/-5.98 Caughell Farms, ON, CA). The experimental protocol was approved by our institutional animal care committee and followed the ARRIVE guidelines.24Animals were treated as per the “Guide for the Care and Use of Laboratory Animals”. All animals received humane care in compliance with the Principles of Laboratory Animal Care formulated by the National Society for Medical Research and the Guide for the Care and Use of Laboratory Animals prepared by the Institute of Laboratory Animal Resources.