Features | KMP | KLA | MLT | Congenital Hemangioma | LIC |
Platelets | ↓↓↓ | ↓↓↓ | ↓↓ - ↓↓↓ | ↓ | ↔ - ↓↓ |
Fibrinogen | ↓ - ↓↓ | ↓ - ↓↓ | ↔ | ↔ - ↓ | ↔ - ↓↓ |
D-dimer | ↑ - ↑↑ | ↑ - ↑↑ | ↔ | ↔ - ↑ | ↑↑ - ↑↑↑ |
Other distinguishing features | Enlarges after birth; infiltrative | Involves multiple sites and organs | Lungs, skin and GI tract primarily | Does not enlarge after birth; may involute rapidly | Worsens with manipulation of malformation; pain and/or palpable phleboliths; at risk for VTE |
Bleeding risk | Minimal | High | High | Minimal | High with procedures |