Key Clinical Message:
Pre-septal cellulitis is a serious diagnosis that can progress to post-septal cellulitis leading to grave consequences. Clinically, viral, and bacterial cellulitis can be indistinguishable from each other. Using rapid DNA/RNA sequencing can be helpful
Introduction :
Preseptal cellulitis is a soft tissue infection that develops secondary to trauma, coryza or local skin inflammation. Infections are usually bacterial with hemophilus influenzae, staphylococci, and streptococci being the most common pathogens.1,2 Although viruses are rarely implicated in the etiology, varicella is known to cause preseptal cellulitis via an eyelid infection without prior respiratory involvement. Rarely, adenovirus eye infections are complicated by bulbar cellulitis. Herein, we present a case of a young man with an adenovirus associated preseptal cellulitis diagnosed by pooled meta-genomic testing and successfully treated with topical steroids.