Effects of creatine supplementation on LDH concentration
As outlined in Figure 3 and Table 3 , our preliminary
analysis indicated that creatine supplementation have no significant
effect in serum LDH concentration compared to placebo (WMD = -5.99; 95%
CI: -14.49, 2.50; P= 0.167). Also, significant heterogeneity was observed
among studies (P= 0.014, I2 = 47.2 %). Some of
subgroup analysis showed that creatine consumption resulted in a
significant reduction in LDH concentrations in trials with 48 hours
measurement of LDH after exercise and >20 g/day creatine
consumption.