Treatment Protocol
The treatment protocol was designed as an intralesional injection of 40 mg methylprednisolone to the maximum curvature point; this injection was repeated once a week for 8 weeks. No local anesthesia was performed before injection, but patients were allowed to use non-steroidal anti-inflammatory drugs and pain killers after injection. A 23G needle was used for injection. The dosage was 40 mg of the drug in its pure form (no dilution), which was loaded into a syringe and then inserted into the plaque at a right angle. The drug was then injected at different points of the plaque by slightly moving the needle around the injection point.
During the protocol, treatment was terminated and the patient was excluded from the study in cases of an unexpected side effects or worsening disease symptoms. All adverse events were recorded during the study period. All procedures were performed by a single experienced urologist.
All patients voluntarily signed their consent to participate in the study. The study was approved by the Ethics Committee of Eskişehir Osmangazi University Faculty of Medicine.