Conclusions

The present study offers a unique prospective and robust assessment of the safety of pertussis vaccination during pregnancy and provides reaffirming evidence of the safety of maternal pertussis vaccination for both mothers and their infants. Evidence presented in our study provide further reassurance to expecting women and healthcare providers about the safety of pertussis vaccination during pregnancy and supports recommendations for pertussis vaccination during pregnancy to prevent morbidity and mortality associated with early-infant pertussis disease. The study findings also aid evidence-based decision making for clinicians and policy makers in countries considering implementation of universal maternal pertussis immunisation programs.