Validation data extraction and analysis
To verify the results of the meta-analysis, all laboratory-confirmed
COVID-19 cases in two hospitals in Wenzhou (the First and Second
affiliated Hospitals of Wenzhou Medical University) from January 22 to
February 22, 2020 were included. Follow-up was performed until
discharge, death, or March 16, 2020. The basic characteristics of the
patients were extracted and compared between severe and non-severe
cases.
We extracted the following information: (1) Demographic characteristics,
including age, gender, height and weight. According to Chinese adult
obesity standards, patients were classified as obese (BMI≥28.0),
overweight (24.0≤BMI<28.0), normal (18.5≤BMI<24.0),
and lean (BMI<18.5) 15. (2) Wuhan exposure
history: the patients were divided into four groups: direct exposure to
Wuhan (the patient recently lived or visited Wuhan); indirect contact
with Wuhan (close contact with people who had been to Wuhan during the
epidemic); contact with other confirmed diagnoses patients; no clear
history of contact. (3) Clinical symptoms, onset to hospitalization
time.