Data extraction
We extracted following required data using a pre-designed standardized
electronic form (Excel, Microsoft Office): first author’s name,
publication year and country, research design, age and gender of
subjects, sample size, duration of intervention and soy dose. Also, we
extracted mean and standard deviation (SD) of plasma adipokines status
(adiponectin and leptin) at baseline and after the intervention. Any
reported standard errors of mean (SEM), were converted to SDs through
following formula by SD = SEM × √n (n is the number of participants in
each group). Finally, in studies which reported data in graphical
figures, data extraction was performed by using GetData Graph Digitizer
2.24 29.