Results:
A total of 37 patients were enrolled and included in the study: 15
patients with IUGR consisted the study group and 22 patients with AGA
fetus consisted the control group. Maternal characteristics and
obstetric outcomes of the study groups are resented in table 1. Maternal
age, parity and BMI were comparable between the groups (table 1). As
expected, patients in the IUGR group were delivered earlier compared to
the controls (36.7 vs 37.7 weeks, p=0.04) and the mean neonatal birth
weight was significantly lower among the IUGR group compared with the
normal controls (1634 ± 428 grams vs 2785 ± 587 grams respectively,
p<0.01).
The results of endothelial function assessment are described in table 2.
The median gestational age at EndoPAT test was 32 weeks in both groups
(table 2). Systolic and diastolic blood pressure did not differ between
the two groups at the time of endothelial function assessment (113 vs
110 mmHg, p= 0.08; 74 vs 67 mmHg, p=0.06, respectively). The median RHI
value was significantly lower in the IUGR group compared with the normal
control group (1.31 vs 1.47 respectively, p=0.04). All women in the IUGR
group had an abnormal RHI value (<1.67), compared with 68% of
the control group (p=0.056).