Conclusion
In conclusion, the low risk result of cfDNA screening is acceptable for
patients with NT between 95th and
99th percentile. Therefore, cfDNA screening in
pregnant women with NT between 95th and
99th percentile may be considered as an acceptable
alternative to invasive test for women intending to avoid the risk of
miscarriage, although the procedure related risks of miscarriage after
CVS and amniocentesis are low (0.1%) [26].