Abbreviations
C674, Cys674; Col I, collagen type I; Col III, collagen type III; CsA, cyclosporin A; DAPI, 4’,6-diamidino-2-phenylindole; FPKM, expected number of fragments per kilobase of transcript sequence per millions base pairs sequenced; HE, hematoxylin/eosin; ICAM1, intercellular adhesion molecule 1; LDLR−/−, LDL receptor-deficient; MYOCD, myocardin; NFAT, nuclear factor of activated T-lymphocytes; OPN, osteopontin; PDTC, pyrrolidinedithiocarbamic acid; S674, Ser674; SERCA, sarco/endoplasmic reticulum calcium ATPase; SKI, SERCA2 C674S knock-in; SMCs, smooth muscle cells; VCAM1, vascular cell adhesion molecule 1; VVG, Verhoeff-Van Gieson; WT, wild-type