Survival Outcome
Although the mean OS and CSS was shorter in cases with
BMI>29.9kg/m2 compared with other BMI groups (74.2 vs. 84.4
and 94.2 months for OS, 97.5 vs. 105.1 and 101.0 months for CSS,
respectively), the differences were not statistically significant
(p=0.532 and p=0.309, respectively) (Figure 1). A Cox
proportional hazards model was used to evaluate the potential predictors
for OS and CSS and the results are shown in Table 5 . Analysis
revealed that OS and CSS was significantly associated with
“Lymphovascular invasion” (HR: 2.17, 95% CI: (1.30-3.60); p=0.003
(OS), HR: 2.55, 95% CI: (1.30-4.98); p=0.006 (CSS) ). In multivariate
analysis, “pN+: N2” (HR: 4.80, 95% CI: (2.79-8.24); p<0.001
(OS), HR: 4.11, 95% CI: (1.90-8.90); p<0.001 (CSS)) was found
to be the independent prognostic factor for OS and CSS. The association
between increased BMI and mortality was not statistically significant in
analysis (p>0.05). Although the mean RFS and MFS was
shorter in cases with BMI>29.9kg/m2 compared with other BMI
groups, there was no statistically significant difference between BMI
groups in terms of RFS and MFS (p=0.751 and p=0.213 respectively)