Conclusion
The finding of this study showed that IL-1, IL-6, IL-8 and neopterin
levels in blood of patients with NMIBC were similar to the levels of
healthy controls. Although the IL-6 and IL-8 levels did not change after
TURBT and intravesical BCG instillation, the IL-1 and neopterin levels
significantly decreased after TURBT. But this reductions in the IL-1 and
neopterin levels did not continue after intravesical BCG instillation.
In conclusion, our findings demonstrated that the IL-1 and neopterin
levels decrease after TURBT due to the decrease in tumor weight or tumor
removal. We suggest further studies that will investigate IL-1 and
neopterin in long term follow-up after TURBT.