Univariate Regression
Age remained significantly associated with IRAF on univariate regression analysis (OR 3.21, p = 0.002). Ibrutinib dose remained significantly associated with IRAF (OR -2.30, p = 0.025). E/e’ and PALS were both significantly associated with IRAF on univariate regression modeling (OR = 2.1, p = 0.04; OR = -2.7, p = 0.01, respectively). Neither PACS or conduit strain were significantly associated with IRAF on univariate regression.