Conclusions:
Age, ibrutinib dose, E/e’, and PALS on pre-treatment echocardiogram were
significantly associated with development of IRAF. On multivariate
regression analyses, age, PALS and PACS remained significantly
associated with IRAF. Impaired LA mechanics add to the assessment of
patients at risk for IRAF.
Keywords :
- Echocardiography
- Left atrial strain
- Atrial fibrillation
- Ibrutinib
- Tyrosine kinase inhibitor
- B-cell malignancies