Systematic reviews characterizing the inconsistency in outcome
reporting
Thirty-nine systematic reviews characterizing the inconsistency in
outcome reporting were identified (table S4)(45-83) including: 16 (41%)
in benign gynaecology and subfertility, 12 (31%) in pregnancy and
childbirth, 6 (15%) in newborn and neonatal health and five (13%) in
oncology. Of these, 25 (64%) were included as part of COS development
and the remaining 14 registered as standalone reviews (table S5). The
variation in outcome reporting was considerable: for example, a review
of intrauterine growth restriction trials identified 238 outcomes and a
review of bladder pain syndrome trials identified only five.(46, 58)