2.3 Enrichment analyses in biological process and KEGG pathway of
intersection targets
Using the R-language packages, such as ”ClusterProfiler”,
”ReactomePA”, ”org.Hs.eg.Db” and ”GOplot” in the R language (3.6.1), the
enrichment analysis and visualization of the biological process and KEGG
pathways of the intersection targets were performed and obtained
accordingly. Moreover, information of gene annotation resulted from
”org.Hs.eg.Db”, p-value Cutoff = 0.05, q-value Cutoff = 0.05 for
enrichment prior to plotting the corresponding bubble chart, histogram
and Circos circle chart [24-25].