2.3 Enrichment analyses in biological process and KEGG pathway of intersection targets
Using the R-language packages, such as ”ClusterProfiler”, ”ReactomePA”, ”org.Hs.eg.Db” and ”GOplot” in the R language (3.6.1), the enrichment analysis and visualization of the biological process and KEGG pathways of the intersection targets were performed and obtained accordingly. Moreover, information of gene annotation resulted from ”org.Hs.eg.Db”, p-value Cutoff = 0.05, q-value Cutoff = 0.05 for enrichment prior to plotting the corresponding bubble chart, histogram and Circos circle chart [24-25].