Introduction
A crisis like the COVID-19 pandemic since last December, is a major public health event that leads to significant uncertainty. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is a distinct clade from the beta coronaviruses associated with human severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS)1. It has infected more than 6.5 million people, claiming over 383 thousands lives in 207 countries and 5 continents as of Jun 2020. The number of COVID-19 infected pregnant women is also increasing. There is legitimate concern, however, that pregnant women might have a different disease course and outcomes, due to the physiological changes in respiratory and immunological systems.
At present, scarce data has compared the difference of the clinical characteristics of pregnant with non-pregnant patients with COVID-19 based on the data from systematic comparisons between infected pregnant and non-pregnant women. This retrospective, single-center and case-control study systematically compared the clinical course and outcomes of pregnant patients with control cases confirmed to have SARS-CoV-2 infection, and also offered some details of drug therapies of pregnant patients from the view of clinical practice. We hope our study findings will provide some novel and valuable information for clinicians under the COVID-19 pandemic and possibly improve the clinical outcomes of infected pregnant women.