Study design and participants
Pre-work permits were obtained by the Turkish Ministry of Health and the local ethics committee of Siirt University (decision no: 2020/05.02). Patients hospitalized in Siirt State Hospital between April and May 2020 and whose COVID-19 PCR (Polymerase Chain Reaction) test was positive were included in the study. Also, a control group was formed from 50 healthy individuals. Urine potential of hydrogen (pH), specific gravity (SG), leukocyte, erythrocyte, protein, nitrite, glucose, and bacteria were recorded by asking the patients for a full urine examination. The patient group was divided into four (mild, moderate, severe, and critical) groups according to the Diagnostic Treatment Program of New Coronavirus Pneumonia (seventh trial version). Patients with the mild group were excluded from the study because they were treated, outpatient.
Patients who were thought to affect the study results, such as chronic kidney failure, asthma, HT, DM, and chronic obstructive pulmonary disease (COPD) were excluded. Also, all patient groups had nitrite negative in urine and no bacteria. Therefore patients with urinary tract infections were excluded from the study. We compared the patient group with healthy controls. Besides, the severe and critical groups in the patient group were combined to determine the severe group, and the moderate group was defined as the non-severe group.