Study design and participants
Pre-work permits were obtained by the Turkish Ministry of Health and the
local ethics committee of Siirt University (decision no: 2020/05.02).
Patients hospitalized in Siirt State Hospital between April and May 2020
and whose COVID-19 PCR (Polymerase Chain Reaction) test was positive
were included in the study. Also, a control group was formed from 50
healthy individuals. Urine potential of hydrogen (pH), specific gravity
(SG), leukocyte, erythrocyte, protein, nitrite, glucose, and bacteria
were recorded by asking the patients for a full urine examination. The
patient group was divided into four (mild, moderate, severe, and
critical) groups according to the Diagnostic Treatment Program of New
Coronavirus Pneumonia (seventh trial version). Patients with the mild
group were excluded from the study because they were treated,
outpatient.
Patients who were thought to affect the study results, such as chronic
kidney failure, asthma, HT, DM, and chronic obstructive pulmonary
disease (COPD) were excluded. Also, all patient groups had nitrite
negative in urine and no bacteria. Therefore patients with urinary tract
infections were excluded from the study. We compared the patient group
with healthy controls. Besides, the severe and critical groups in the
patient group were combined to determine the severe group, and the
moderate group was defined as the non-severe group.