Figure Legends:
Figure 1 Electrocardiogram on arrival shows sinus tachycardia, with inferior Q waves, poor R wave progression and non-specific ST-segment changes
Figure 2a) Coronary angiogram showing a right dominant circulation without any obstructive disease noted in the right coronary artery 2b) Antero-posterior cranial view showing bifurcation of left main into left anterior descending and circumflex arteries without any obstructive coronary artery disease noted throughout the length of left anterior descending artery 2c) Antero-posterior caudal view showing absence of obstructive coronary artery disease in the circumflex territory 2d) Left ventriculogram showing severe hypokinesis of the apical segments with apical ballooning and basal hyperkinesis, changes consistent with classical Takotsubo cardiomyopathy.
Figure 3 Electrocardiogram on arrival shows sinus rhythm symmetric deep T wave inversions in the precordial leads and inferior ST changes
Figure 4a) Coronary angiogram showing a right dominant circulation without any significant disease in the right coronary artery 4b) Antero-posterior cranial view showing a myocardial bridge in the mid-left anterior descending artery without any obstructive coronary artery disease 4c) Left anterior oblique cranial view showing bifurcation of the left main in left anterior descending and circumflex arteries, with no significant obstructive disease noted in the circumflex distribution 4d) Left ventriculogram showing severe hypokinesis of the apical segments with apical ballooning and basal hyperkinesis during systole, changes consistent with classical Takotsubo cardiomyopathy
Supplementary Video 1 Parasternal long-axis view of the echocardiogram for the second case shows preserved basal wall motion and apical hypokinesis.
Supplementary Video 2 Apical three-chamber view of the echocardiogram for the second case confirms apical and mid-apical antero-septal hypokinesis.