Burkitt lymphoma involvement was detected in the bone marrow aspiration and biopsy. Finally, our patient was diagnosed with stage IV Burkitt lymphoma. The child was treated with the B-cell non-Hodgkin lymphoma treatment protocol of intensive systemic chemotherapy. Successful supportive treatment consisting of hydration, xanthine oxidase inhibitor (allopurinol), and urine alkalization with sodium bicarbonate were quickly applied for tumor lysis syndrome in our Hematology-Oncology Department. After 6 cycles of intensive chemotherapy treatment, the child patient has been followed in remission for 5 years.