SAA: Severe Allergic Asthma; SAR: Seasonal Allergic Rhinitis; PAA: Perennial Allergic Asthma; PAR: Perennial Allergic Rhinitis; ARC: Allergic Rhino-Conjunctivitis
NR: No Reference; SC: Subcutaneous; Symptom Severity: 1=mild, 2=moderate, 3=severe ¥ In the Okubo 2020 trial all patients received concomitant antihistamines and nasal corticosteroids as standard of care treatment *Standard of care treatment + placebo