Bullet point summary
What is already known
Sinapic acid has been reported to have a neuroprotective effect in a 6-hydroxydopamine-induced animal model of parkinsonism.
What this study adds
Sinapic acid protected against MPTP-induced parkinsonism through REV-ERB α-modulated mitochondrial fission.
Clinical significance
Sinapic acid could be a promising clinical candidate for the treatment of Parkinson’s disease.