Demographics, Comorbidities, and ADI
Mean clinical follow-up was 5.1 ± 2.1 years (Table 1 ) and median ATAA size on index CT scan was 4.3 (4.1, 4.5) cm (Table 2 ), and were similar between ADI quartiles. The mean age of the study population was 69.6 ± 9.2 years old, with the most disadvantaged quartile (Q4) being significantly younger (p=0.04). The majority of patients were male (77.8%), and there were no differences in the proportions of sex between quartiles. Race was predominately White (73.1%) but Black race was more common in more disadvantaged quartiles (p<0.001).
COPD was more prevalent in the most disadvantaged quartile (N=31, 27%), ranging from 13-16% in the lower ADI quartiles (p=0.02). There were also significant differences in presence of bicuspid aortic valve (BAV) and mitral valve pathologies between quartiles, but without clear directionality of these trends (p=0.03 and p=0.049, respectively). There were no significant differences between quartiles for other comorbidities obtained. Connective tissue disease was only present in 5 patients and was not included in statistical modeling.