Median follow-up (years) |
2.40 (1.48-3.93) |
3.17
(1.92-4.92) |
0.02 |
Baseline AS grade |
|
|
>0.9 |
Mild |
120 (68%) |
40 (68%) |
|
Moderate |
57 (32%) |
19 (32%) |
|
AS grade at last follow-up |
|
|
0.062 |
None |
8 (4.5%) |
7 (12%) |
|
Mild |
50 (28%) |
15 (25%) |
|
Moderate |
69 (39%) |
15 (25%) |
|
Severe |
50 (28%) |
22 (37%) |
|
Baseline Mean Gradient (mmHg) |
16 (13-20) |
18 (14-22) |
0.2 |
Baseline Peak Velocity (m/s) |
2.70 (2.50-3.00) |
2.80
(2.50-3.11) |
0.5 |
Baseline Aortic Valve Area (cm2) |
1.30 (1.10-1.60) |
1.35
(1.18-1.70) |
0.2 |
Baseline AVA Index (cm2/m2) |
0.72 (0.59-0.86) |
0.70
(0.60-0.82) |
0.7 |
Progression Rate of Mean Gradient (mmHg/year) |
2.3 (0.6-5.0) |
1.5 (0.5-4.1) |
0.5 |
Progression Rate of Peak Velocity (m/s/year) |
0.14 (0.00-0.31) |
0.10 (0.04-0.26) |
0.7 |
Progression of AS grade |
105 (59%) |
40 (68%) |
0.2 |
Rapid Progressors (>2.85mmHg/year) |
74 (43%) |
21 (36%) |
0.4 |