Statistical analysis
For human data, differences between groups were analysed using the
Wilcoxon signed rank test. For mouse data, differences between two
groups and between three groups were analysed using the Mann–WhitneyU test and Steel–Dwass test, respectively. When p-values less
than 0.05, differences between means were considered to be statistically
significant. All analyses and calculations were performed using
JMP® Pro version 13.0.0 software (SAS Institute, Inc.,
Cary, NC, USA).