There are three transmission elements of
infectious diseases : source of infection, route of transmission and
susceptible population. The maternal immune system of pregnant women is
in a dilemma that it need to establish immunologic tolerance to the
allogeneic fetus, while to defend the bodies from the invasion of
pathogenic microorganisms. The maternal immunological states keep being
in flux through the pregnant progress. Pregnancy drives women into a
partial immune deficiency state[3]. It takes for
granted that pregnant women own more possibility of infection on account
of the COVID-19.Whereas some latest Chinese
researches[1, 4, 5]drew the conclusion that
pregnant women presented the equal opportunity of COVID-19 infection,
compared with non-pregnant patients. This consequence shocks the common
sense of the public, but still it may come to light if more cases are
analyzed and geographic limitation is ruled out. Several evidences could
prove the infection insurability between mothers and fetuses. We must
keep vigilant to its potential risks. Researches prove that infection
could activate the immune system and rise the level of some immune
factors such as TNF-α and IL-17a, which could lead to brain development
abnormalities, preterm labor, even fetal loss[6,
7].And fever as the most common and initial symptom of COVID-19
infection could be associated with increased
attention-deficit/hyperactivity disorder in the
offspring[3].