Etiology of covid-19:
Common HCoV-OC43 (human CoVs), along with HCoV-HKU1 (betaCoVs of the A
lineage, HCoV-NL63 along with) HCoV-229E (alphaCoVs) Wu, J et al (2020).
These types of viruses can leads to the common colds as well as
self-limiting type of upper respiratory infections in the individuals
having immune system capable of fighting against them (immunocompetent)
Hong, H et al (2020). In the individuals having weak immune system and
could not compete the invading pathogens as immunocompromised in
addition to the aged, the infections of the lower respiratory tract can
arise Xiong, Y et al (2020).The members of this hefty family of the
viruses can be a source of the respiratory, hepatic, enteric, along with
those of the neurological disorders in diverse of animals species,
together with those of camels, cats, cattle in addition to bats
Shekerdemian, L et al (2020). Up to now, (HCoVs) human CoVs with seven
different types are competent of infecting those of the humans have been
recognized Qiao and J (2020). On the whole, the estimates recommend that
those of two percent of the people are well with the carriers as
of the CoV along with that these types of viruses are accountable in
favor of having acute respiratory infections are 5% to 10% Henry, B et
al (2020).Consequently, SARS-CoV-2 type of virus belongs to the betaCoVs
group. It has shape as may be round or those of elliptic furthermore it
is frequently pleomorphic (occurrence in various distinct forms)
,moreover, with the diameter about 60–140 nm. It is also sensitive to
heat and UV (ultraviolet) radiations like other viruses from this group.
Also the high temperature can also use to limit the replication of
viruses Li, L et al (2020). At present, the temperature that inactivates
SARS-CoV-2 ought to be well explained and its inactivation temperature
is about 27° C.In contrast, it may oppose the cold temperature yet
underneath 0°C Fang, L et al (2020). Additionally, these types of
viruses can be efficiently made inactivated by the lipid types of
solvents as, chlorine-containing disinfectant, ether (75%),
ethanol, chloroform along with, peroxyacetic acid etc Chen, L et al
(2020). Other types of the human CoVs as SARS-CoV, SARS-CoV-2, in
addition to MERS-CoV (betaCoVs of the B along with C lineage,
correspondingly) Surveillances and V (2020). They can be a source of the
epidemics through inconsistent medical sternness it the features of
respiratory along with extra-respiratory events. Pertaining to MERS-CoV
and SARS-CoV, the transience rates are up to 11% and 36%,
correspondingly Filatov, V et al (2020).In genetic stipulations, have
confirmed that new HCoV genome, secluded as of a number of patient
having the pneumonia which is atypical as subsequent to having a visit
to Wuhan, they had about 89% nucleotide characteristics similar by
means of those as that present in bat SARS-like-CoVZXC21 along with 82%
as those of human SARS-CoV that’s why it is called SARS-CoV2 Zu, Z et al
(2020). It has a RNA genome with 29891 nucleotides that encodes for
those of 9 In genetic stipulations, have confirmed that new HCoV genome,
secluded as of a number of patient having the pneumonia which is
atypical as subsequent to having a visit to Wuhan, they had about 89%
nucleotide characteristics similar by means of those as that present in
bat SARS-like-CoVZXC21 along with 82% as those of human SARS-CoV that’s
why it is called SARS-CoV2 Sun, P et al (2020). It has a RNA genome with
29891 nucleotides that encodes for those of 9860 amino acids. Possibly,
a number of SARS-CoV-2 subsists. Even though the source of the
SARS-CoV-2 is not completely tacit, but the genomic analysis put forward
the evidence as the SARS-CoV-2 mainly evolved as of a strain present in
bats Gao, J et al (2020). The probable amplifying mammalian host,
transitional between those of bats as well as humans, unknown. As the
alterations in novel strain may possibly encompass unswervingly
triggered to the virulence in the humans Cascella, M et al (2020).