3.4 Mid-term outcomes
The overall 5-year survival rate was 35.1% across the entire cohort;
51.1% in group N, and 29.5% in group Y (log-rank test, group N vs.
group Y, p=0.26; Figure 1A). The 5-year freedom from cardiac events rate
was 66.7% across the entire cohort; 69.5% in group N, and 66.0% in
group Y (log-rank test, group N vs. group Y, p=0.68; Figure 1B). In
terms of 5-year freedom from cardiac death, the rate was 88.7% across
the entire cohort; 100% in group N, and 84.6% in group Y (Figure 1C).
In total, 36 remote deaths occurred across the entire cohort, with 7 in
group N and 29 in group Y. The causes of remote death in group N were
pneumonia in 3 patients, other infectious disease in 3, and malignancy
in 1, with no cardiac deaths. On the other hand, the major causes in
group Y were cardiac death in 8 patients, pneumonia in 8,
cerebrovascular disease in 3, malignancy in 2, and other causes in 8.