Covid19 components
SARS-CoV-2 is a single-stranded virus with the genome size is 29.891 kb
long(29891 nucleotides) encoding 9860 amino acids(Cai, Tu et al. 2020).
which belongs to genus Coronavirus and
family Coronaviridae (Chan, Kok, et al. 2020). With the Virion
size that ranging from 70 to 90 nm Spike, membrane, and envelope surface
viral proteins of coronavirus are embedded in host membrane-derived
lipid bilayer encapsulating the helical nucleocapsid comprising viral
RNA. The genome comprises of 6–11 open reading frames (ORFs) with 5′
and 3′ flanking untranslated regions (UTRs) (Kumar, Nyodu, et al. 2020).
classified into the subfamily Coronavirinae that consists of four
genera Alphacoronavirus (αCoV ),Betacoronavirus (βCoV), Gammacoronavirus (γCoV),
and Deltacoronavirus (δCoV) (Cui, Li et al. 2019). As in the
figure, 1 showed the high-resolution crystal structure of the virus and
depicted the external components that contain four structural proteins,
namely envelope (E), spike (S), membrane (M), and nucleocapsid (N). The
S, M, and E proteins together form the envelope of the
virus, positive-sense, spherical to pleomorphic particles, measuring
between 80 and 160 nm in length(Xia, Liu, et al. 2020).