Patient data
From January 2005 to May 2017, 439 patients underwent MV surgery at our department. A MIVT procedure was done in 250 patients between July 2008 and May 2017, and 189 patients were operated through conventional sternotomy between January 2005 and December 2014. Pre-, intra- and postoperative data were retrospectively retrieved from the patient’s medical records. Organ-specific biomarkers were obtained preoperatively and per 24 hour on ICU concerning assessment of liver, kidney and myocardial damage, while lung and brain function were based on clinical parameters such as ventilation time and stroke incidence respectively. Evaluation of systemic inflammatory response was based on CRP values, obtained preoperatively and at the first and second day after surgery. Use of blood products, postoperative blood loss and hematological assessment were additionally included.
The clinical follow-up ended in November 2017, considering the endpoints survival, reoperation free-survival and late MV function.