1 INTRODUCTION
COVID-19 (Coronavirus disease), caused by severe acute respiratory
coronavirus 2 syndrome (SARS-CoV-2), was first identified in Wuhan ,
China, in December 2019(1). The World Health Organization declared a
public health emergency of international concern regarding this global
outbreak of pneumonia on 30 January 2020. Globally, as of 9:37am CEST,
30 May 2020, there have been 5,796,257 confirmed cases of COVID-19,
including 362,483deaths, reported to WHO(2). In Bangladesh, as of 4 June
2020, there have been about 52000 confirmed cases of COVID-19 with about
700 deaths. The virus COVID-19 is primarily transmitted between humans
through respiratory droplets and contact routes. Analysis of 75,465
COVID-19 cases in China has not reported airborne transmission(3-5).
Early moderate signs occurred during the course of the disease offer a
chance to early detect COVID-19. Fast identification and accurate
treatment have been critical to avoiding the spread of infection(6, 7).
At present, transcription polymerase chain reaction (RT-PCR) and
real‐time RT-PCR (rRT‐PCR) are used to detect gene expressions of SARS
CoV-2. There are three genes expression of SARS CoV-2 such as the
RNA-dependent RNA polymerase (RdRp)/helicase (Hel), spike (S), and
nucleocapsid (N) genes(8, 9). In Bangladesh, rRT-PCR is used to detect
early COVID-19. After a week, point-of-care test kits for Ag and Ab is
used to measure the protective level of plasma antibodies ( IgM and
IgG). In this study, we reported COVID-19 case of man who had no travel
history to COVID-19 prone areas whereas he had the characteristics signs
and symptoms of COVID-19. Chest X-ray and rRT-PCR revealed his confirmed
COVID-19.